ホーム>>ML-252 (hydrochloride)

ML-252 (hydrochloride)

カタログ番号GC44219

ML-252は、電圧依存性カリウムチャネルサブタイプKv7.2の強力で選択的な阻害剤です(パッチクランプアッセイにおけるIC50 = 69 nM)。

Products are for research use only. Not for human use. We do not sell to patients.

ML-252 (hydrochloride) 化学構造

サイズ 価格 在庫数 個数
1mg
$57.00
在庫あり
5mg
$157.00
在庫あり
10mg
$283.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com

顧客レビュー

カスタマーレビューに基づきます。

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

ML-252 is a potent and selective inhibitor of the voltage-gated potassium channel subtype Kv7.2 (IC50 = 69 nM in a patch clamp assay). It is the (S)-enantiomer and is more potent than the (R)-enantiomer and the racemic mixture (IC50s = 944 and 160 nM, respectively). It is selective for Kv7.2 over other Kv channel subtypes, >68 G protein-coupled receptors, transporters, L- and N-type calcium channels, and KATP and hERG potassium channels though it does inhibit the melatonin MT1 receptor 61% when used at a concentration of 10 µM.

レビュー

Review for ML-252 (hydrochloride)

Average Rating: 5 ★★★★★ (Based on Reviews and 38 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for ML-252 (hydrochloride)

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.