Prostaglandin A2-biotin (Synonyms: PGA2biotin) |
| カタログ番号GC44705 |
プロスタグランジンA2（PGA2）は、NIH 3T3細胞のG1およびG2 / M期における細胞周期進行を阻害します。
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Prostaglandin A2 (PGA2) blocks cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. It has antitumor effects, targeting scaffold/matrix attachment region-binding protein 1 (SMAR1) through an Hsp70-dependent mechanism. PGA2 also induces apoptosis in HL-60 cells. Prostaglandin A2-biotin (PGA2-biotin) is an affinity probe which allows PGA2 to be detected through an interaction with the biotin ligand. Biotinylated eicosanoids have been used to capture proteins which interact with the lipid.
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