CAY10573 |
| カタログ番号GC43174 |
ペルオキシソーム増殖因子活性化受容体（PPAR）は、脂質によって活性化される転写因子であり、代謝異常の治療のための薬剤ターゲットとしてしばしば使用されます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 853652-40-1
Sample solution is provided at 25 µL, 10mM.
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The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARα, γ, and δ with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPARα, γ, and δ with EC50 values of 8, 70, and 500 nM, respectively. CAY10573 demonstrates stronger binding and functional activity for PPARγ than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM).
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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