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CCR1 antagonist 8 (Synonyms: CCR1 antagonist 8)

カタログ番号GC31893

第3のアザインダゾール系化合物であるCCR1拮抗薬8(化合物19n)はCCR1拮抗薬であり、Ca2+フラックスアッセイでIC50は1.8nMである。

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CCR1 antagonist 8 化学構造

Cas No.: 1295298-26-8

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

CCR1 antagonist 8 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist clinical candidate, with an IC50 of 1.8 nM in Ca2+ flux assay[1].

[1]. Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg Med Chem Lett. 2019 Feb 1;29(3):441-448.

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