Cholesteryl Acetate (Synonyms: 3β-acetoxy-5-Cholestene, 3β-hydroxy-5-Cholestene 3-acetate, Cholesteryl Acetic Acid, NSC 8799)

Cholesteryl acetate is a cholesterol ester.¹ It has been used as an internal standard for the quantification of cholesterol, as well as cholesterol derivatives, by GC or GLC.^2,3 Cholesteryl acetate has also been derivatized from, and used for the quantification of, cholesterol by ESI-MS/MS.⁴ It has also been used in the manufacturing of liquid crystal displays (LCDs), wrist watches, and thermometers.⁵

1.Huang, Z., Kawi, S., and Chiew, Y.C.Solubility of cholesterol and its esters in supercritical carbon dioxide with and without cosolventsJ. Supercrit. Fluids30(1)25-39(2004) 2.Jones Owen, V.M., Ho, F.K., Mazzuchin, A., et al.Cholesterol in amniotic fluid, determined by gas chromatographyClin. Chem.22(2)224-226(1976) 3.Gray, G.M., and Yardley, H.J.Lipid compositions of cells isolated from pig, human, and rat epidermisJ. Lipid Res.16(6)434-440(1975) 4.Liebisch, G., Binder, M., Schifferer, R., et al.High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS/MS)Biochim. Biophys. Acta176(1)121-128(2006) 5.Vijayakumar, V.N., Rajasekaran, T.R., and Baskar, K.Influence of hydrogen bond on thermal and phase transitions of binary complex liquid crystalsRuss. J. Phys. Chem. A91(13)2578-2584(2017)