Dehydroascorbic acid (Synonyms: L-Dehydroascorbic Acid, DHAA) |
| カタログ番号GC33746 |
デヒドロアスコルビン酸、ビタミン C の血液脳関門輸送可能なフォームは、実験的脳卒中における強力な脳保護を仲介します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 490-83-5
Sample solution is provided at 25 µL, 10mM.
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Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.
Neuronal injury in ischemic stroke is partly mediated by cytotoxic reactive oxygen species. Although the antioxidant ascorbic acid (AA) or vitamin C does not penetrate the blood-brain barrier (BBB), its oxidized form, dehydroascorbic acid (DHA), enters the brain by means of facilitative transport[1].
[1]. Huang J, et al. Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potentcerebroprotection in experimental stroke. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11720-4.
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