Dehydroascorbic acid (Synonyms: L-Dehydroascorbic Acid, DHAA) |
| Katalog-Nr.GC33746 |
DehydroascorbinsÄure, eine durch die Blut-Hirn-Schranke transportierbare Form von Vitamin C, vermittelt eine starke Hirnprotektion bei experimentellem Schlaganfall.
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Cas No.: 490-83-5
Sample solution is provided at 25 µL, 10mM.
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Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.
Neuronal injury in ischemic stroke is partly mediated by cytotoxic reactive oxygen species. Although the antioxidant ascorbic acid (AA) or vitamin C does not penetrate the blood-brain barrier (BBB), its oxidized form, dehydroascorbic acid (DHA), enters the brain by means of facilitative transport[1].
[1]. Huang J, et al. Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potentcerebroprotection in experimental stroke. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11720-4.
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