Desacetyl Bisacodyl (Synonyms: DAB, DDPM) |
| カタログ番号GC43412 |
デサセチルビサコジル（DAB）は、ビサコジルとナトリウムピコスルフェートの2つの刺激性下剤の有効な代謝物質です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 603-41-8
Sample solution is provided at 25 µL, 10mM.
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Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate. DAB evokes several effects at the colon or rectum, including increased mucus and chloride secretion. Oral administration of bisacodyl leads to decreased expression of aquaporin-3 in the colon of rats. The effects of both DAB and bisacodyl can be blocked with cyclooxygenase (COX) inhibitors, suggesting that products of the COX signaling pathway contribute to laxative effects.
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