Desmethyl cariprazine |
| カタログ番号GC62926 |
デスメチル カリプラジンは、カリプラジンの活性代謝物です 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 839712-15-1
Sample solution is provided at 25 µL, 10mM.
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Desmethyl cariprazine is an active metabolite of Cariprazine[1]. Cariprazine, an antipsychotic drug candidate, exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM)[2].
[1]. Campbell RH, et al. Review of cariprazine in management of psychiatric illness. Ment Health Clin. 2018 Mar 23;7(5):221-229.
[2]. Seneca N, et al. Occupancy of dopamine D2 and D3 and serotonin 5-HT1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology (Berl). 2011 Dec;218(3):579-8.
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