Dimethyl L-glutamate (Synonyms: Dimethyl glutamate) |
| カタログ番号GC66836 |
グルタミン酸の膜透過性類似体であるジメチル L-グルタミン酸 (ジメチル グルタミン酸) は、グルコースによって誘導されるインスリン放出を刺激することができます。 L-グルタミン酸ジメチルは、KATP チャネルの活性を抑制します。 L-グルタミン酸ジメチルは E. gracilis の増殖を阻害し、異常な細胞分裂を引き起こします。 L-グルタミン酸ジメチルは、糖尿病、グルコース輸送、リン酸化、およびさらなる代謝の研究に使用できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6525-53-7
Sample solution is provided at 25 µL, 10mM.
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Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the KATP channel activities. Dimethyl L-glutamate inhibits E. gracilis growth and causes abnormal cell division. Dimethyl L-glutamate can be used in the research of diabetes, glucose transport, phosphorylation, and further metabolism[1][2][3][4].
[1]. J Cancelas, et al. Potentiation by glutamic acid dimethyl ester of GLP-1 insulinotropic action in fed anaesthetized rats. Int J Mol Med. 2001 Nov;8(5):531-2.
[2]. Sener A, et al. Insulinotropic action of glutamic acid dimethyl ester. American Journal of Physiology-Endocrinology and Metabolism, 1994, 267(4): E573-E584.
[3]. I S Owens, et al. Induction of abnormal cell division in Euglena gracilis by glutamic diethyl ester. J Protozool. 1969 May;16(2):211-5.
[4]. Hidenori Katsuta, et al. Insulinotropic action of glutamate is dependent on the inhibition of ATP-sensitive potassium channel activities in MIN 6 beta cells. Biochem Biophys Res Commun. 2003 Nov 21;311(3):660-4.
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