ELA-14 (human) |
| カタログ番号GC50410 |
強力なアペリン作動薬；ELA-32の生物活性フラグメント
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1886973-05-2
Sample solution is provided at 25 µL, 10mM.
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Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32 . Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo. ELA-14 negative control (Cat.No. 6294) also available.
Murza et al (2016) Discovery and structure-activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions. J.Med.Chem. 59 2962 PMID:26986036
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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