FPL 62064 |
| カタログ番号GC39013 |
FPL 62064 は強力な 5-リポキシゲナーゼ (5-LOX) および COX 二重阻害剤であり、RBL-1 サイトゾル 5-リポキシゲナーゼおよびプロスタグランジン合成酵素 (シクロオキシゲナーゼ) の IC50 値はそれぞれ 3.5 μM および 3.1 μM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 103141-09-9
Sample solution is provided at 25 µL, 10mM.
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FLP 62064 is a potent 5-lipoxygenase (5-LOX) and COX-2 dual inhibitor. FLP 62064 has potently anti-inflammatory activity[1][2].
[1]. Blackham A, et al. FPL 62064, a topically active 5-lipoxygenase/cyclooxygenase inhibitor. Agents Actions. 1990 Jun;30(3-4):432-42. [2]. Shabaan MA, et al. Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase. Arch Pharm (Weinheim). 2020 Feb 7:e1900308.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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