H-Tyr-Ile-Gly-Ser-Arg-OH |
カタログ番号GA22975
One-Click Copy Product Info
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ラミニンB1鎖のドメインIII内に位置するペンタペプチドYIGSRは、ラミニンにおける主要な受容体結合部位を表します。細胞表面受容体と競合することで、この短いペプチドは基底膜への細胞付着を阻害し、腫瘍転移の形成を防止することができます。YIGSRはまた、腫瘍細胞の移動を促進し、さらに様々な上皮細胞がラミニンに対して接着するための媒介物質でもあります。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 110590-64-2
Sample solution is provided at 25 µL, 10mM.
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The pentapeptide YIGSR located within domain III of the laminin B1 chain, represents a major receptor binding site in laminin. By competing with laminin for the cell surface receptor, the short peptide is able to inhibit cell attachment to basement mem
| Cas No. | 110590-64-2 | SDF | |
| Formula | C26H42N8O8 | M.Wt | 594.67 |
| 溶解度 | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.6816 mL | 8.408 mL | 16.816 mL |
| 5 mM | 336.3 μL | 1.6816 mL | 3.3632 mL |
| 10 mM | 168.2 μL | 840.8 μL | 1.6816 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)