Z-Gly-Pro-pNA (Synonyms: Carbobenzoxy-glycyl-L-prolyl-p-Nitroanilide, N-CBZ-Glycyl-L-proline 4-Nitroanilide, Z-Gly-Pro-4-Nitroanilide) |
カタログ番号GA23825
One-Click Copy Product Info
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Z-Gly-Pro-pNAは、プロリルエンドペプチダーゼに切断できる発色基質である。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 65022-15-3
Sample solution is provided at 25 µL, 10mM.
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Z-Gly-Pro-pNAは、プロリルエンドペプチダーゼに切断できる発色基質である[1]。プロリルエンドペプチダーゼの酵素活性は、0.1Mのクエン酸/リン酸二ナトリウム緩衝液（pH 7）におけるZ-Gly-Pro-pNAの切断後、410nmにおける吸光度の増加から決定されたのであり、反応を60℃で行った[2]。Z-Gly-Pro-pNAは、Thermococcus kodakarensisからのグルテン分解プロリルエンドペプチダーゼの速度論パラメーターの特徴付けに広く使われている[3]。
| Cas No. | 65022-15-3 | SDF | |
| 同義語 | Carbobenzoxy-glycyl-L-prolyl-p-Nitroanilide, N-CBZ-Glycyl-L-proline 4-Nitroanilide, Z-Gly-Pro-4-Nitroanilide | ||
| Formula | C21H22N4O6 | M.Wt | 426.43 |
| 溶解度 | Soluble in DMSO | Storage | Store at -20°C |
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 2.3451 mL | 11.7253 mL | 23.4505 mL |
| 5 mM | 469 μL | 2.3451 mL | 4.6901 mL |
| 10 mM | 234.5 μL | 1.1725 mL | 2.3451 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.50% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)