Bilobetin |
| カタログ番号GC35518 |
イチョウの有効成分であるビロベチンは、血中脂質を低下させ、インスリンの効果を改善します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 521-32-4
Sample solution is provided at 25 µL, 10mM.
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Bilobetin, an active component of Ginkgo biloba, can reduce blood lipids and improve the effects of insulin. Bilobetin ameliorated insulin resistance, increased the hepatic uptake and oxidation of lipids, reduced very-low-density lipoprotein triglyceride secretion and blood triglyceride levels, enhanced the expression and activity of enzymes involved in β-oxidation and attenuated the accumulation of triglycerides and their metabolites in tissues. Bilobetin also increased the phosphorylation, nuclear translocation and activity of PPARα accompanied by elevated cAMP level and PKA activity[1]. PPARα PKA
[1]. Kou XH, et al. Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet. Br J Pharmacol. 2012 Apr;165(8):2692-706.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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