Fibronectin CS1 Peptide |
カタログ番号GC36042 |
接続セグメント 1 (CS-1) は、フィブロネクチンのタイプ III ホモロジー接続セグメント (IIICS) に位置する細胞接着ドメインです。フィブロネクチン CS1 ペプチドは、Arg-Gly-Asp を含むドメインを欠いており、自発的および実験的転移モデルで腫瘍転移を積極的に阻害します。
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Cas No.: 136466-51-8
Sample solution is provided at 25 µL, 10mM.
The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models[1].
[1]. Saiki I, et al. Inhibition of lung metastasis by synthetic and recombinant fragments of human fibronectin with functional domains. Jpn J Cancer Res. 1990 Oct;81(10):1003-11.
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