Fibronectin CS1 Peptide |
| Katalog-Nr.GC36042 |
Das Verbindungssegment 1 (CS-1) ist eine ZellanhaftungsdomÄne, die sich im Typ-III-Homologie-Verbindungssegment (IIICS) von Fibronectin befindet. Dem Fibronektin-CS1-Peptid fehlt die Arg-Gly-Asp-haltige DomÄne, es hemmt aktiv Tumormetastasen in spontanen und experimentellen Metastasierungsmodellen.
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Cas No.: 136466-51-8
Sample solution is provided at 25 µL, 10mM.
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The connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models[1].
[1]. Saiki I, et al. Inhibition of lung metastasis by synthetic and recombinant fragments of human fibronectin with functional domains. Jpn J Cancer Res. 1990 Oct;81(10):1003-11.
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