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Gallopamil

カタログ番号GC36105

ベラパミルのメトキシ誘導体であるガロパミル (メトキシベラパミル) は、フェニルアルキルアミンのカルシウム拮抗薬です 。

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Gallopamil 化学構造

Cas No.: 16662-47-8

サイズ 価格 在庫数 個数
10mM (in 1mL DMSO)
$144.00
在庫あり
5mg
$135.00
在庫あり
10mg
$225.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Gallopamil (Methoxyverapamil), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. Gallopamil acts on the vascular system and the heart and nodal structure[1]. Gallopamil inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM[2]. Ca2+

[1]. Brogden RN, et al. Gallopamil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in ischaemic heart disease. Drugs. 1994 Jan;47(1):93-115. [2]. Sewing KF, et al. Calcium channel antagonists verapamil and gallopamil are powerful inhibitors of acid secretion in isolated and enriched guinea pig parietal cells. Pharmacology. 1983;27(1):9-14.

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Average Rating: 5 ★★★★★ (Based on Reviews and 27 reference(s) in Google Scholar.)

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