Pemafibrate racemate |
カタログ番号GC36867 |
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Cas No.: 848258-31-1
Sample solution is provided at 25 µL, 10mM.
Pemafibrate racemate is the racemate of pemafibrate, and activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively. h-PPARα|1 nM (EC50)|h-PPARδ|1.7 μM (EC50)
Pemafibrate racemate activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively[1].
[1]. Yamazaki Y, et al. Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4689-93. Epub2007 May 24.
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