Incensole Acetate (Synonyms: Incensol Acetate) |
| カタログ番号GC38213 |
酢酸インセンソールは、ボスウェリア カルテリ樹脂の主成分であり、外傷性および虚血性頭部外傷における神経損傷に対する神経保護効果があります。
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Cas No.: 34701-53-6
Sample solution is provided at 25 µL, 10mM.
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Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25-35-triggered apoptosis in hOBNSCs[1].
Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25-35-induced cell death, a 48-52% decrease in cell viability at Aβ25-35 is restored to 85-89% upon pre-treatment with IA[1].Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25-35 in hOBNSCs[1]. Cell Viability Assay[1] Cell Line: Human olfactory bulb neural stem cells
[1]. El-Magd MA, et al. Incensole acetate prevents beta-amyloid-induced neurotoxicity in human olfactory bulb neural stem cells. Biomed Pharmacother. 2018 Sep;105:813-823.
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