Incensole Acetate (Synonyms: Incensol Acetate) |
| Katalog-Nr.GC38213 |
Incensoleacetat ist ein Hauptbestandteil von Boswellia carterii-Harz und hat neuroprotektive Wirkungen gegen neuronale SchÄden bei traumatischen und ischÄmischen Kopfverletzungen.
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Cas No.: 34701-53-6
Sample solution is provided at 25 µL, 10mM.
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Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25-35-triggered apoptosis in hOBNSCs[1].
Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25-35-induced cell death, a 48-52% decrease in cell viability at Aβ25-35 is restored to 85-89% upon pre-treatment with IA[1].Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25-35 in hOBNSCs[1]. Cell Viability Assay[1] Cell Line: Human olfactory bulb neural stem cells
[1]. El-Magd MA, et al. Incensole acetate prevents beta-amyloid-induced neurotoxicity in human olfactory bulb neural stem cells. Biomed Pharmacother. 2018 Sep;105:813-823.
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