VUF11207 fumarate |
| カタログ番号GC38217 |
VUF11207 フマル酸塩は、CXCR7 に特異的に結合する CXCR7 アゴニストです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1785665-61-3
Sample solution is provided at 25 µL, 10mM.
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VUF11207 fumarate (Compound 29) is a CXCR7 agonist and a high-potency CXCR7 (pKi of 8.1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7[1].
[1]. Wijtmans M, et al. Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists. Eur J Med Chem. 2012 May;51:184-92.
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