Glutaminase-IN-3 |
カタログ番号GC62285 |
フェロスタチン-1 (Fer-1) 類似体である SRS11-92 は、強力なフェロトーシス阻害剤です。 SRS11-92 は、HT-1080 ヒト線維肉腫細胞でエラスチンによって誘導されるフェロトーシス細胞死を阻害します (EC50=6 nM)。
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Cas No.: 1439399-45-7
Sample solution is provided at 25 µL, 10mM.
Glutaminase-IN-3 (compound 657) is a potent glutaminase inhibitor with an IC50 of 0.24 μM for Glutaminase 1 (GLS1). Glutaminase-IN-3 is extracted from patent WO2014089048A1, compound 657[1].
[1]. Mark K. Bennett, et al. Treatment of cancer with heterocyclic inhibitors of glutaminase. WO2014089048A1.
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