ホーム>>Peptides>>Histone H3K27Me2 (21-44)-GK-biotin (trifluoroacetate salt)

Histone H3K27Me2 (21-44)-GK-biotin (trifluoroacetate salt) (Synonyms: ATKAAR-K(Me2)-SAPATGGVKKPHRYRPG-GK(Biotin), Histone H3 (21-24) (Lys27me2)-GK(Biotin), Lys(Me2)27-Histone H3 (21-44)-GK(Biotin) (trifluoroacetate salt))

カタログ番号GC43847

Histone H3K27Me2(21-44)-GK-biotinは、ヒトヒストンH3.1およびH3.2配列のアミノ酸残基22〜45に対応するヒストンH3のペプチドフラグメントです。

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Histone H3K27Me2 (21-44)-GK-biotin (trifluoroacetate salt) 化学構造

サイズ 価格 在庫数 個数
250μg
$255.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Histone H3K27Me2 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences. It is dimethylated at lysine 27 and biotinylated via a C-terminal GK linker. Dimethylation of H3K27 is present on large chromatin domains across approximately 70% of total histone H3 and prevents firing of non-cell type-specific enhancers. H3K27Me2 accumulates in gene bodies of genes with low levels of expression in mouse embryonic stem cells. Histone H3K27Me2 (21-44)-GK-biotin has been used as a positive control in a high-throughput screen for inhibitors of the histone demethylase jumonji AT-rich interactive domain 1B (JARID1B).

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