HS024 TFA |
カタログ番号GC63770 |
HS024 は選択的 MC4 受容体アンタゴニストであり、MC4、MC5、MC3、および MC1 の Kis はそれぞれ 0.29、3.29、5.45、18.6 nM です。
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Sample solution is provided at 25 µL, 10mM.
HS024 is a selective MC4 receptor antagonist, with Kis of 0.29, 3.29, 5.45, 18.6 nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake[1].
[1]. Kask A, et al. Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo. Endocrinology. 1998;139(12):5006-5014.
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