HU-331 (Synonyms: Cannabidiolquinone) |
カタログ番号GC41298 |
内因性カンナビノイドは、中枢カンナビノイド(CB1)、末梢カンナビノイド(CB2)および非-CB受容体介在薬理学の豊富なシステムを有しており、記憶、減量と食欲、神経変性疾患、腫瘍監視、鎮痛作用および炎症など多くの分野での研究を促進しています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 137252-25-6
Sample solution is provided at 25 µL, 10mM.
The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation. HU-331 is a hydroxylquinone cannabidiol analog that exhibits potent antineoplastic activity on a variety of human cancer cell lines. It effectively inhibits the growth of human Raji and Jurkat lymphoma cells in vitro with an EC50 of approximately 0.2 µg/ml and an EC80 of 1.56 µg/ml. HU-331 also inhibits the growth of HT-29 colon carcinoma cells, which have been inoculated into nude mice, by more than 50% at a dose of 5 mg/kg.
Average Rating: 5
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