Hydrocarbon chain derivative 1 (6,6'-Oxybis[2,2-dimethyl-1-hexanol]) (Synonyms: 6,6'-Oxybis[2,2-dimethyl-1-hexanol]) |
| カタログ番号GC31542 |
炭化水素鎖誘導体 1 (6,6'-オキシビス[2,2-ジメチル-1-ヘキサノール]) は、脂質合成に対する阻害活性を持つ活性化合物です。
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![Hydrocarbon chain derivative 1 (6,6'-Oxybis[2,2-dimethyl-1-hexanol]) 化学構造](/media/struct/GC3/GC31542.png "Hydrocarbon chain derivative 1 (6,6'-Oxybis[2,2-dimethyl-1-hexanol]) 化学構造")
Cas No.: 300762-25-8
Sample solution is provided at 25 µL, 10mM.
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Hydrocarbon chain derivative 1 is an active compound, with inhibitory activities against lipid synthesis.
Hydrocarbon chain derivative 1 is well tolerated with mild liver effects at 2000 mg/kg in rats[1]. Hydrocarbon chain derivative 1 shows inhibitory effect on lipid synthesis, with an IC50 of 11 μM[2].
[1]. Oniciu DC, et al. Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids. J Med Chem. 2006 Jan 12;49(1):334-48. [2]. Oniciu DC, et al. Long hydrocarbon chain diols and diacids with central ether or ketone moieties that favorably alter lipid disorders. Pharmazie. 2006 Feb;61(2):157-65.
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