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Isochlortetracycline (Synonyms: 7-Chloroisotetracycline, Isoaureomycin)

カタログ番号GC18649 Copy One-Click Copy Product Info

イソクロルテトラサイクリンは、広範囲に作用する抗生物質であるクロルテトラサイクリンの不活性なアルカリ分解生成物です。

Products are for research use only. Not for human use. We do not sell to patients.

Isochlortetracycline 化学構造

Cas No.: 514-53-4

サイズ 価格 在庫数 個数
1mg
$88.00
在庫あり
5mg
$339.00
在庫あり
10mg
$548.00
在庫あり

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顧客レビュー

カスタマーレビューに基づきます。

Sample solution is provided at 25 µL, 10mM.



Description of Isochlortetracycline

Isochlortetracycline is an inactive alkaline degradation product of the broad-spectrum antibiotic chlortetracycline. This molecule appears to be a product of in vivo chlortetracycline metabolism with epimerization rates exceeding >50%, and high levels can be detected in the yolks of eggs from chickens exposed to this antibiotic. Isochlortetracycline is used as a reference standard in chromatographic analyses of chlortetracycline and its metabolic derivatives.

Chemical Properties of Isochlortetracycline

Cas No. 514-53-4 SDF
同義語 7-Chloroisotetracycline, Isoaureomycin
Chemical Name (4S,4aS,6S,8aS)-6-[(1S)-7-chloro-1,3-dihydro-4-hydroxy-1-methyl-3-oxo-1-isobenzofuranyl]-4-(dimethylamino)-1,4,4a,5,6,7,8,8a-octahydro-3,8a-dihydroxy-1,8-dioxo-2-naphthalenecarboxamide
Canonical SMILES O=C([C@@](C(C(C(N)=O)=C(O)[C@H]1N(C)C)=O)(O)[C@@]1([H])C2)C[C@@]2([H])[C@]3(C)OC(C4=C3C(Cl)=CC=C4O)=O
Formula C22H23ClN2O8 M.Wt 478.9
溶解度 DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Isochlortetracycline

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0881 mL 10.4406 mL 20.8812 mL
5 mM 417.6 μL 2.0881 mL 4.1762 mL
10 mM 208.8 μL 1.0441 mL 2.0881 mL
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In vivo Formulation Calculator (Clear solution) of Isochlortetracycline

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 10 reference(s) in Google Scholar.)

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