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ISX 9 (Synonyms: Isoxazole 9, Neuronal Differentiation Inducer III)

カタログ番号GC10472

ISX 9 (イソオキサゾール 9) は、成体神経幹細胞分化の強力なインデューサーです。

Products are for research use only. Not for human use. We do not sell to patients.

ISX 9 化学構造

Cas No.: 832115-62-5

サイズ 価格 在庫数 個数
10mg
$102.00
在庫あり
50mg
$232.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

ISX-9 is a small molecule inducer of adult neural stem cell differentiation. Target: At 2.5-20 μM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test.

References:
[1]. Petrik D, et al. Functional and mechanistic exploration of an adult neurogenesis-promoting small molecule. FASEB J. 2012 Aug;26(8):3148-3162.

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Average Rating: 5 ★★★★★ (Based on Reviews and 28 reference(s) in Google Scholar.)

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