Lecanoric Acid (Synonyms: NSC 249981) |
| カタログ番号GC18190 |
レカノール酸は、真菌から分離されたヒスチジン脱炭酸酵素阻害剤です。
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Cas No.: 480-56-8
Sample solution is provided at 25 µL, 10mM.
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Lecanoric acid is a naturally occurring depside polyphenol isolated from a variety of lichens. It is a potent antioxidant, surpassing ascorbic acid in a 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging assay (IC50s = 424.51 and 6.42 μg/ml for lecanoric and ascorbic acid, respectively). Lecanoric acid has antibacterial and antifungal activities with minimum inhibitory concentrations ranging from 0.5 to 1 mg/ml for a panel of fifteen microorganisms. In a cell viability assay, lecanoric acid exhibits antiproliferative activity against HeLa cells (IC50 = 123.97 μg/ml). Lecanoric acid also exhibits antidiabetic and hypolipidemic properties.
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