MK-0429 (L-000845704) (Synonyms: L-000845704) |
カタログ番号GC32055 |
MK-0429 (L-000845704) (L-000845704) は、α の IC50 値が 1.6 nM、2.8 nM、0.1 nM、0.7 nM、0.5 nM および 12.2 nM である、経口活性、強力、選択的、非ペプチド パン インテグリン アンタゴニストです。 ;vβ1, αvβ3, αvβ5, αvβ6, αvβ8 and α5β1, respectively.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 227963-15-7
Sample solution is provided at 25 µL, 10mM.
MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (α5β1 integrin) and 2.8 nM (αvβ3 integrin), respectively.
[1]. Zhou X, et al. An integrin antagonist (MK-0429) decreases proteinuria and renal fibrosis in the ZSF1 rat diabetic nephropathy model.Pharmacol Res Perspect. 2017 Oct; 5 (5).
Average Rating: 5
(Based on Reviews and 31 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *