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MMP-8 Inhibitor I (Synonyms: Matrix Metalloproteinase-8 Inhibitor I)

カタログ番号GC18616

MMP-8阻害剤Iは、IC50値が4nMの好中球コラーゲナーゼマトリックスメタロプロテアーゼ-8(MMP-8)の選択的な阻害剤です。

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MMP-8 Inhibitor I 化学構造

Cas No.: 236403-25-1

サイズ 価格 在庫数 個数
1mg
$284.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products
MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. This inhibitor does not target the activities of other MMPs in vitro. MMP-8 cleaves interstitial collagens and has exhibited activity in atherosclerotic plaques, angiogenesis, and stem cell mobilization. Additionally, MMP-8 expression is observed in normal mammary epithelial cells, whereas a loss of expression is observed in human ductal carcinoma in situ and the deletion of MMP-8 accelerates tumor onset in a mouse model of aggressive breast cancer.

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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