N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ) |
| カタログ番号GC33916 |
N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ) は、強力なエンジイン抗腫瘍抗生物質です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 108212-76-6
Sample solution is provided at 25 µL, 10mM.
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N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic. Target: AntibacterialN-Acetyl-Calicheamicin is a a derivative of Calicheamicin. Calicheamicin is a naturally occurring hydrophobic enediyne antibiotic that was isolated from the actinomycete Micromonospora echinospora calichensis. Calicheamicin can interfere with biological processes not simply by cleaving free DNA but also by displacing a DNA-binding protein through competition or modulation of DNA structure.
[1]. Stasi R, et al. Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia. Cancer Treat Rev. 2008 Feb;34(1):49-60.
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