N-Cyclohexanecarbonyltetradecylamine |
| カタログ番号GC44340 |
多数の脂肪酸エタノールアミド類は、内因性カンナビノイドの固有の生物学的活性を増強します。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1215071-05-8
Sample solution is provided at 25 µL, 10mM.
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Numerous analogs of fatty acyl ethanolamides potentiate the intrinsic biological activity of endocannabinoids. This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty acid amide hydrolase (FAAH) within the neurons. However, Ueda, et al. has recently cloned another amidase, the acidic PEAase that promotes the hydrolysis of palmitoylethanolamide. N-Cyclohexanecarbonyltetradecylamine is an analog of N-cyclohexanecarbonyl-pentadecylamine, a selective inhibitor of acidic PEAase with an IC50 value of 4.5 µM, that contains 1 less carbon in the alkyl chain. The biological activity of N-cyclohexanecarbonyltetradecylamine has not been documented.
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