NH2-PEG3-C2-Boc |
| カタログ番号GC64315 |
NH2-PEG3-C2-Boc は、PROTAC の合成に使用できる PEG ベースの PROTAC リンカーです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 252881-74-6
Sample solution is provided at 25 µL, 10mM.
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NH2-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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