Nw-Propyl-L-arginine hydrochloride (Synonyms: N-omega-Propyl-L-arginine hydrochloride) |
| カタログ番号GC50011 |
N&ω;-プロピル-L-アルギニン (N-ω-プロピル-L-アルギニン) 塩酸塩は、神経細胞の一酸化窒素合成酵素 (nNOS) の強力で競合的かつ高度に選択的な阻害剤であり、Ki は 57 nM です。
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Cas No.: 2321366-46-3
Sample solution is provided at 25 µL, 10mM.
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Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.
Kakoki et al (2001) The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am.J.Physiol.Regul.Integr.Comp.Physiol. 281 R91 PMID:11404282 |Zhang et al (1997) Potent and selective inhibition of neuronal nitric oxide synthase by Nω-propyl-L-arginine. J.Med.Chem. 40 3869 PMID:9397167
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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