PD 174265 |
| カタログ番号GC44585 |
PD 174265 は、450 pM の IC50 を持つ強力な細胞透過性、可逆性、および選択的な EGFR 阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 216163-53-0
Sample solution is provided at 25 µL, 10mM.
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PD 174265 is a potent, cell-permeable inhibitor of the tyrosine kinase activity of the epidermal growth factor (EGF) receptor (IC50 = 0.45 nM). It is effective in cells, blocking tyrosine phosphorylation induced by either EGF or heregulin (IC50s = 39 and 220 nM, respectively). The action of PD 174265 is reversible, which makes it a useful tool for comparative studies with irreversible inhibitors of EGFR kinase activity.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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