Phomopsinamine (Synonyms: Phomopsinamine A) |
| カタログ番号GC48394 |
微小管の重合を阻害する物質
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Cas No.: 89085-54-1
Sample solution is provided at 25 µL, 10mM.
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Phomopsinamine is an inhibitor of microtubule polymerization and a derivative of phomopsin A .1 It inhibits the rate and extent of polymerization of tubulin isolated from ovine brain (IC50s = 0.53 and 0.59 µM, respectively).
1.Lacey, E., Edgar, J.A., and Culvenor, C.C.Interaction of phomopsin A and related compounds with purified sheep brain tubulinBiochem. Pharmacol.36(13)2133-2138(1987)
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