Pralidoxime iodide |
| カタログ番号GC39656 |
ヨウ化プラリドキシムは、アセチルコリンエステラーゼ (AChE) の強力な再活性化剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 94-63-3
Sample solution is provided at 25 µL, 10mM.
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Pralidoxime iodide is a reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent, which inhibits AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning[1][2].
[1]. Cadieux CL, et al. Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents. Chem Biol Interact. 2016;259(Pt B):133‐141. [2]. Eyer P, Buckley N. Pralidoxime for organophosphate poisoning. Lancet. 2006;368(9553):2110‐2111. [3]. HouzÉ P, et al. High Dose of Pralidoxime Reverses Paraoxon-Induced Respiratory Toxicity in Mice. Turk J Anaesthesiol Reanim. 2018;46(2):131‐138.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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