Pravastatin lactone (Synonyms: R-414, SQ 31,369) |
| カタログ番号GC44676 |
プラバスタチンラクトンは、メバスタチンの環水酸化代謝物であり、ヒドロキシメチルグルタリル補酵素A（HMG-CoA）還元酵素阻害剤であるプラバスタチンの代謝産物です。
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Cas No.: 85956-22-5
Sample solution is provided at 25 µL, 10mM.
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Pravastatin lactone is a metabolite of pravastatin , a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that is a ring-hydroxylated metabolite of mevastatin . Pravastatin lactone is formed when pravastatin undergoes acid-catalyzed non-enzymatic lactonization in the stomach following oral administration.
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