Psoromic Acid (Synonyms: NSC 92186, Parellic Acid) |
| カタログ番号GC18547 |
ソロミック酸は、Rabジェラニルゲラニルトランスフェラーゼの阻害剤です（IC50 = 1.3 uM）。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7299/11/8
Sample solution is provided at 25 µL, 10mM.
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Psoromic acid is an inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 uM) and P. falciparum fatty acid synthesis (FAS) II. It shows cytotoxic effects on primary rat cerebral cortex and human cancer U87MG cell lines in vitro (IC50s = 79.40 and 56.22 mg/L, respectively). It also is cytotoxic against human KB cancer cells (IC50 = 31.6 uM). It shows moderate activity against liver stage P. beghei (IC50 = 31.6 uM) and drug-resistant blood stage P. falciparum (IC50 = 29.2 uM). The maximum tolerated dose in zebrafish larvae is 15.5 uM.
Review for Psoromic Acid
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)
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