Quinapril HCl (Synonyms: CI-906, PD 109452-2) |
| カタログ番号GC12368 |
キナプリル (塩酸塩) (CI-906) は、アンジオテンシン変換酵素 (ACE) 阻害薬クラスに属するプロドラッグです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 82586-55-8
Sample solution is provided at 25 µL, 10mM.
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Quinapril (hydrochloride) (CI-906) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.
Quinapril (hydrochloride) (CI-906) is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure. Quinapril is rapidly de-esterified after absorption to quinaprilat (the active diacid metabolite), a potent angiotensin converting enzyme (ACE) inhibitor[1][2].
References:
[1]. Song, J.C. and C.M. White, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clin Pharmacokinet, 2002. 41(3): p. 207-24.
[2]. Culy, C.R. and B. Jarvis, Quinapril: a further update of its pharmacology and therapeutic use in cardiovascular disorders. Drugs, 2002. 62(2): p. 339-85.
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