(S,R,S)-AHPC-PEG5-COOH (Synonyms: VH032-PEG5-COOH; VHL Ligand-Linker Conjugates 16; E3 Ligase Ligand-Linker Conjugates 58) |
| カタログ番号GC60009 |
(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) は、(S,R,S)-AHPC ベースの VHL リガンドと 5 ユニット PEG リンカーを組み込んだ合成 E3 リガーゼ リガンド-リンカー コンジュゲートです。 PROTAC テクノロジーで使用されます。
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Cas No.: 2172820-14-1
Sample solution is provided at 25 µL, 10mM.
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(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].
[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.
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