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S1QEL1.1 (Synonyms: S1QEL)

カタログ番号GC44860

S1QEL1.1は、ミトコンドリア呼吸鎖複合体IのIQサイトを介した逆電子伝達中にスーパーオキシド生成を抑制する小分子です(IC50 = 70 nM)。酸化的リン酸化に影響を与えずに作用します。

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S1QEL1.1 化学構造

Cas No.: 897613-29-5

サイズ 価格 在庫数 個数
500μg
$60.00
在庫あり
1mg
$114.00
在庫あり
5mg
$479.00
在庫あり
10mg
$839.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation. It diminishes endogenous oxidative damage in primary astrocytes, reduces stress-induced signaling in a cardiomyocyte cell model, and protects against ischemia-reperfusion injury in perfused mouse heart.

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Average Rating: 5 ★★★★★ (Based on Reviews and 36 reference(s) in Google Scholar.)

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