TA 02 |
| カタログ番号GC11635 |
SB 203580 の類似体である TA 02 は、IC50 が 20 nM の p38 MAPK 阻害剤です。
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Cas No.: 1784751-19-4
Sample solution is provided at 25 µL, 10mM.
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TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: p38TA-02 is a novel compound with similar cardiogenic properties asSB203580 and SB202190. TA-02 especially inhibits TGFBR-2.
References:
[1]. Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.
[2]. Filip LACO, et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO 2015119579 A1.
Average Rating: 5 (Based on Reviews and 16 reference(s) in Google Scholar.)
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