tBPC |
| カタログ番号GC50440 |
NPY Y4受容体の陽性アロステリック調節因子
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1942-71-8
Sample solution is provided at 25 µL, 10mM.
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Positive allosteric modulator of neuropeptide Y receptor 4 (Y4R). Potentiates Y4R response to pancreatic polypeptide (PP), neuropeptide Y (NPY) and peptide YY (PYY) (EC50 values are 0.03, 0.4 and 0.5 nM respectively). Shows selectivity for Y4R over Y1R, Y2R and Y5R.
Schubert et al (2017) Identification and characterization of the first selective Y4 receptor positive allosteric modulator. J.Med.Chem. 60 7605 PMID:28795803
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