Termitomycamide B |
| カタログ番号GC45014 |
エンドプラズミック・レチクル（ER）ストレスは、誤折りたんぱく質の蓄積とカルシウムホメオスタシスの破壊によって引き起こされ、パーキンソン病、アルツハイマー病、プリオン病を含むいくつかの神経性疾患に関連しています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1254277-89-8
Sample solution is provided at 25 µL, 10mM.
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Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson's, Alzheimer's, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites Termitomycamide B is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin.
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