TH 1217 (Synonyms: ZINC1775962367) |
| カタログ番号GC50483 |
TH 1217 (ZINC1775962367) は、強力かつ選択的な dCTPase ピロホスファターゼ 1 (dCTPase) 阻害剤であり、IC50 は 47 nM です。
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Cas No.: 1862212-48-3
Sample solution is provided at 25 µL, 10mM.
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Potent dCTPase pyrophosphatase 1 inhibitor (IC50 = 47 nM). TH 1217 is not stable in aqueous solution. It is recommended that fresh samples are prepared and used immediately.
Llona-Minguez et al (2016) Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1. J.Med.Chem. 59 1140 PMID:26771665
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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