Thiamine (hydrochloride) (Synonyms: Aneurine, Vitamin B1) |
| カタログ番号GC45031 |
チアミンは、抗酸化作用、神経保護作用、抗不安作用を持つ水溶性ビタミンです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1967/3/8
Sample solution is provided at 25 µL, 10mM.
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Thiamine is a water-soluble vitamin with antioxidant, neuroprotective, and anxiolytic properties. It inhibits lipid peroxidation in rat liver microsomes and free radical oxidation of oleic acid in vitro when used at concentrations ranging from 1 to 100 μM. In vivo, thiamine (100 mg/kg) reduces hepatic levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), lipid peroxidation, and protein damage in a rat model of acute ethanol intoxication. It reverses predator stress-induced suppression of hippocampal neurogenesis and decreases the latency of step-down from a platform, indicating anxiolytic-like activity in mice. Thiamine (8.5 mg/100 g food) reduces neurodegeneration and increases survival in Slc19a3-/- mice, a model of thiamine metabolism dysfunction syndrome-2 (THMD-2).
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
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