Tributyrin |
| カタログ番号GC61349 |
中性短鎖脂肪酸トリグリセリドであるトリブチリン (グリセリルトリブチレート) は、安定で急速に吸収される酪酸のプロドラッグです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1960/1/5
Sample solution is provided at 25 µL, 10mM.
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Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects[1].
[1]. T Gaschott, et al. Tributyrin, a stable and rapidly absorbed prodrug of butyric acid, enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells. J Nutr. 2001 Jun;131(6):1839-43. [2]. Claudia P SchrÖder, et al. Tributyrin-induced differentiation promotes apoptosis of LS 174T colon cancer cells in vitro. Int J Oncol. 2002 Jan;20(1):195-200.
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